NegEnt Respiro

NegEnt Respiro is a CE-marked medical device for aerosol therapy that uses a water-soluble micellar emulsion (Terpenololo), formulated as drops and patented by Prof. Tullio Scrimali. Its active ingredient is micellar cannabidiol derived from industrial-variety Cannabis Sativa L. biomass.

This product complies with Article 18 of the Safety Decree (April 2025), since it is obtained from leaves rather than from the inflorescences of industrial Cannabis sativa L.

The innovation of water-soluble micellar CBD, developed in Herbal Neurocare’s laboratories, has enabled the use of CBD for the first time with various types of ultrasonic aerosol devices and delivery modes.

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Individual Inhalation via Mask

Individual inhalation through a mask delivers therapeutic anti-inflammatory and bronchodilator benefits.

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Instructions for Therapeutic Inhalation

Use an ultrasonic aerosol device, dilute 2-4 drops of NegEnt Respiro (20-40 mg of CBD) in 5-6 ml of sterile distilled water, inhale 1-2 times per day for 10-15 minutes per session.

You may use a personal aerosol device with a mask, available on Amazon. Based on long and successful experience, we recommend a portable, silent ultrasonic aerosol device with rechargeable battery, suitable for adults and children.

Environmental Nebulization via Ultrasonic Room Device

NegEnt Respiro can be dispersed in enclosed spaces using ultrasonic humidifiers such as the MegaWise Ultrasonic Cool Mist Humidifier (sold separately on Amazon). This method supports respiratory wellness and, thanks to CBD’s action on the nervous system, produces a calming effect that enhances mood and sleep quality.

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Administration Method and Dosage (Rooms)

Dilute 10 drops (100 mg of CBD) in 300 ml of distilled water for rooms up to 20 m². Increase the dosage proportionally for larger rooms.

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Regulatory Framework

NegEnt Respiro is registered as a Class I CE medical device with the Italian Ministry of Health. Its formulation—cannabidiol extracted via supercritical CO₂ from industrial Cannabis Sativa L.—ensures maximum purity and safety, being completely free of THC, solvents, and contaminants. NegEnt Respiro is designed exclusively for inhalation and not for oral use.

NegEnt Respiro for Pets

Use in Senior Pets with Respiratory and Cardiac Conditions

The endocannabinoid system exists in mammals such as dogs and cats, where CB1 and CB2 receptors influence inflammation, bronchial tone, and stress response. For senior pets with respiratory or cardiac issues, environmental delivery of micellar CBD (Terpenololo) offers a non-invasive way to improve quality of life.

Rationale and Benefits

Micellar CBD nebulized into home environments is passively absorbed by animals, avoiding the stress sometimes caused by oral administration. In senior dogs and cats with respiratory and cardiac challenges, CBD activation of CB2 receptors reduces inflammation and eases breathing. Interaction with CB1 receptors in the central nervous system helps to alleviate anxiety, stabilize heart rhythm, and improve sleep.

Recommended Administration for Animals

  • For Dogs: Nebulize 5-8 drops of NegEnt Respiro (50-80 mg micellar CBD) in 300 ml of distilled water. Place an ultrasonic nebulizer near the kennel for a daily 6-8 hour session.
  • For Cats: In a quiet area, nebulize 3-5 drops of NegEnt Respiro (30-50 mg micellar CBD) in 300 ml of distilled water. Recommended session duration is 4-6 hours per day.
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Purchase NegEnt Respiro

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